Deep vein thrombosis and pulmonary embolism have been described in many patients affected by COVID-19, including young adults without any risk factors. Many doctors have reported that the coagulation abnormalities were atypical, and that heparin wasn’t working in these patients.
In these situations, amputation may sometimes be the only way to treat ischemia. Also, artificial ventilation can be inefficient with pulmonary embolism because of the shunt created by the blood clots.
Ivan Couronne, Issam Ahmed. Blood Clots: Another Bad Surprise From COVID-19. La Presse. April 27, 2020.