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home/Knowledge Base/Public health

Vaccine Development Landscape

46 views 1 04/26/2020 05/20/2020 Noémie Desgagnés

This list shows candidate vaccines and their research stage on May 20th, 2020. 

Candidate vaccines in clinical evaluation: 9
Vaccine  Platform Developer/

Location

Stage
Ad5-nCoV Non-

Replicating Viral Vector

CanSinoBiological Inc./ Beijing Institute of Biotechnology

(China)

Phase II

ChiCTR2000031781 

Phase I

ChiCTR2000030906 

mRNA-1273 RNA Moderna/NIAID

(U.S.)

Phase 2

(IND accepted)

Phase 1

NCT04283461

ChAdOx1 nCoV-19 Non- Replicating Viral Vector University of Oxford

(UK)

Phase I/II

NCT04324606

– Inactivated Wuhan Institute of Biological Products/Sinopharm

(China)

Phase I/II

ChiCTR2000031809

– Inactivated Beijing Institute of Biological Products/Sinopharm Phase 1/II

ChiCTR2000032459

– Inactivated Sinovac Biotech Co.

(China)

Phase I/II

NCT04352608

BNT162 RNA BioNTech/Fosun Pharma/Pfizer

(Germany)

Phase I/II

2020-001038-36

NCT04368728

INO-4800 DNA Inovio Pharmaceuticals

(U.S.)

Phase I

NCT04336410

LV-SMENP Lentiviral Shenzhen Geno-immune Medical Institute Phase I/II

NCT04276896

Pathogen-specific aAPC Lentiviral Shenzhen Geno-Immune Medical Institute Phase I

NCT04299724

 

Candidates vaccines in preclinical evaluation : 109
Protein Subunit 41
RNA 14
Replicating Viral Vector 14
Non-Replicating Viral Vector 13
DNA 9
VLP 7
Inactivated 5
Live Attenuated Virus 3
Unknown  3

 

These data come from a document produced by the World Health Organization and an article by Nature.com identifying the current COVID-19 candidate vaccines. This document will be frequently updated by personal researches on clinicaltrials.gov.  

 

Sources :

  1. Thanh Le T., Andreadakis Z., Kumar A., et al (April 9, 2020) The COVID-19 vaccine development landscape. Nature.com, Retrieved from https://www.nature.com/articles/d41573-020-00073-5
  2. U.S National Library of Medicine. https://clinicaltrials.gov/
  3. World Health Organization. (April 11, 2020) DRAFT landscape of COVID-19 candidate vaccines. Retrieved from  https://www.who.int/blueprint/priority-diseases/key-action/novel-coronavirus/en/
Tags:Vaccine

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