Thrombotic occlusive vasculopathy

1. Llamas-Velasco M. et al. described a 61-year-old male with ischemic digits and retiform purpura and livedoid lesions.

• Nasopharyngeal swab was positive for SARS-CoV-2 infection.
• The patient was admitted to the intensive care unit.
• The lesions involve hands and feet.
• Laboratory results revealed leucopenia, increased fibrinogen, increased D-dimer and a heterozygous Factor V Leiden mutation.

2. Histopathological study show:

• Sweat gland necrosis
• Thrombi and fibrinoid necrosis in the upper dermis vessels and the dermo-hypodermal junction vessels

3. The authors suggested that these lesions were related to an underlying systemic coagulopathy of COVID-19.

Source:

1. Llamas-Velasco M., Munos-Hernandez P., Lazaro-Gonzalez J., et al. (May 14, 2020). Thrombotic occlusive vasculopathy in skin biopsy from a livedoid lesion of a COVID‐19 patient. British Journal of Dermatology. https://doi.org/10.1111/bjd.19222