- Previous studies have shown that CoVs, like SARS-CoV, have a tropism for the central nervous system.
- Due to its high similarity with SARS-CoV, SARS-CoV-2 may also possess a similar neuroinvasive potential, which may partially explain the acute respiratory failure of COVID-19 patients.
Review of past studies on coronaviruses’s propensity for neuroinvasion.
Li YC, Bai WZ, Hashikawa T. (February 27, 2020). The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients. The Journal of Medical Virology. 2020. https://doi.org/10.1002/jmv.25728