- Patients with COVID-19 induced ARDS had a low lung recruitability (measured by R/I ratio) with high PEEP, questionning the necessity of high peep in COVID-19 associated ARDS.
- R/I ratio is a simplified one-breath bedside way of measuring lung recruitability.
- Alternating body position (prone and supine) was associated with a better lung recruitability.
ARDSnet Recommandations for PEEP/FiO2 (Lower PEEP/higher FiO2)
ARDSnet Recommandations for PEEP/FiO2 (Higher PEEP/lower FiO2)
This data come from a retrospective, observational study including 12 patients with COVID-19 induced ARDS admitted to the ICU of Wuhan Jinyintan Hospital in China. Every patient was on mechanical ventilation. They studied whether with a high PEEP the lungs of the patients were recruitable. Chen et al. present a method to characterize lung recruitability at the bedside.
- Chen L, Del Sorbo L, Grieco DL, et al. (January 15, 2020). Potential for Lung Recruitment Estimated by the Recruitment-to-Inflation Ratio in Acute Respiratory Distress Syndrome. A Clinical Trial. Am J Respir Crit Care Med. https://doi.org/10.1164/rccm.201902-0334OC
- Pan C., Chen L., Lu C., et al ( March 23, 2020). Lung Recruitability in SARS-CoV-2 Associated Acute Respiratory Distress Syndrome: A Single-center, Observational Study. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.202003-0527LE
- ARDSnet. Mechanical Ventilation Protocol Summary. Retrieved from: http://www.ardsnet.org/files/ventilator_protocol_2008-07.pdf