- Acute necrotizing encephalopathy (ANE) is a rare complication of influenza and other viral infections and has been related to intracranial cytokine storms.
- A female airline worker in her late fifties is the first reported case of acute necrotizing hemorrhagic encephalopathy associated with SARS-CoV-2.
- Hemorrhagic bithalamic lesions were demonstrated by CT and MRI imagery.
- However, detection of SARS-CoV-2 in the CSF could not be performed.
Poyiadji N., Shahin G., Noujaim D., Stone M., Patel S., Griffith B., (March 31, 2020), COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI, Radiology, https://doi.org/10.1148/radiol.2020201187