This case series demonstrates pernio-like lesions as a manifestation of COVID-19. Patients presenting this skin lesion were generally young, with few comorbidities, and had relatively benign clinical courses. It presented as the sole symptom in 55% of patients. In patients with other COVID-19 symptoms, pernio-like lesions typically appeared concurrently or after other symptoms. Lesions in […]
Although there is evolving evidence suggesting that skin manifestations may occur in some COVID-19 patients, experts are not unanimous. Current data do not allow a clear link between pernio-like lesions and COVID-19. However, due to an increased number of cases in young patients during the pandemic and until the physiopathology is better understood, new onset […]
International League of Dermatological Societies promotes the use of newly developed registries: Dermatology COVID-19 Registries – COVID-19 patients who develop dermatologic manifestations and patients with an existing dermatologic condition who develop COVID-19. PsoProtect– Psoriasis patients who were COVID-19 infected. SECURE-AD– Atopic Dermatitis patients who were COVID-19 infected Society of Pediatric Dermatology promotes a survey collecting […]
Epidemiology : Epidemiological and transmission tendencies are like those seen in non-pregnant adults. Consistent with findings in non-pregnant adults, the cases were predominantly classified as mild or common in terms of severity. Lag time between onset of symptoms and diagnosis was directly related to the severity of the infection. Transmission via the reproductive system […]
Guillain-Barré syndrome has previously been reported in human coronavirus infections.1 A first presumed case of acute Guillain-Barré syndrome “parainfectious” to COVID-19 was described in a 61-year-old woman who initially presented with lower-limb weakness. She developed respiratory symptoms eight days later and was tested positive for SARS-CoV-2 on RT-PCR assay.2 Later, other cases of post-infectious Guillain-Barré syndrome […]
A survey done on the general population during the initial COVID-19 outbreak in China showed 53,8% moderate-to-severe impact on mental health, and 28,8% moderate-to-severe anxiety among respondents. A higher psychological impact, and higher levels of stress, anxiety and depression were found among females, students, respondents with physical symptoms and people with poor self-rated health status. […]
China’s mental health professionals and health authorities are using a variety of online platforms to provide online psychological services during the COVID-19 outbreak. Through online consultations and 24-hour psychological assistance hotlines, mental health professionals provide support, counseling and crisis intervention. Artificial intelligence programs are also used for psychological crisis intervention. Online surveys and blogging sites […]
Longer incubation period was seen in children, thus reinforcing usage of preventive control interventions in time; Majority of positive patients had a confirmed case in their family members; Asymptomatic infections are more frequent than in adults; The most common finding in chest computed tomography (CT scan) was bilateral ground-glass opacity; Patients with pre-existing comorbidities could […]
A progressive lymphopenia < 1000 seems to be associated with a more severe disease; CRP (C-Reactive Protein) appears to be elevated in some cases, but could be explained by bacterial co-infection. Elevated PCT (procalcitonin) levels could also point out to a coinfection and should be included in the blood work. These patients might be more […]
Regarding smoldering multiple myeloma (SMM): Standard-risk patients should be monitored without active intervention, as usual. For high-risk patients, the possibility of enrollment in clinical trials might be limited; consider a conservative approach with close monitoring and observation. Regarding newly diagnosed active multiple myeloma (MM): All patients should be screened for COVID-19 before starting induction therapy. […]
Regarding surveillance and follow-up: Telemedicine appointments should replace routine in-clinic visits whenever possible. Outpatient radiology should remain accessible for patients and providers; radiology departments must establish protocols to limit risk of viral exposure for patients and staff. Regarding treatment and procedures: Consider whether treatment can be reasonably postponed until recovery; if it cannot, appropriate management […]
Regarding surveillance and follow-up: Telephone and telemedicine visits should replace routine in-clinic visits for nearly all patients. Minimize blood tests, scans and prescriptions. Strongly consider delaying routine surveillance scans and colonoscopies, as well as carcinoembryonic antigen (CEA) monitoring. In patients with metastatic disease and abnormal CEA, controlling CEA at intervals that scans would otherwise be […]
Cancer patients who are admitted for treatment (not necessarily active cancer treatment) seem to have increased susceptibility to COVID-19; older patients (>60 years) and patients with NSCLC (non-small cell lung cancer) appear to be at particular risk1. Hospital admissions and recurrent hospital visits, as well as the immunocompromised state of cancer patients undergoing treatment, are […]
Anosmia/hyposmia and ageusia are present in a majority of Covid-19 patients (5, 6) These symptoms are significantly more frequent in COVID-19 patients than influenza patients(1) and influenza-like patients. (6) They usually have an acute onset and commonly present as an initial manifestation. (1,5) Most patients reported complete or partial recovery of smell and taste. (1,6) […]
Regarding baseline risk of infection and death: Smoking history, is correlated with a higher incidence of respiratory infections and a 2.4 times higher risk of ICU admission, mechanical ventilation or death from COVID-19 infection. This may be due to structural and immunologic-induced modifications from tobacco; Alteration in the lung architecture from tumor mechanical obstruction (or […]
