Endocrinology

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Endocrinology

Resources for managing endocrinology patients

5  articles in this collection
Written by Audrey Mathieu, Jane Wang, 

The Use of Corticosteroids in Adrenal Insufficiency

The World Health Organization has recently advised against corticosteroids use in COVID-19 patients, unless indicated for another reason, as in adrenal insufficiency (AI). Indeed, both patients with primary or secondary AI are at higher risk of developing infections, precipitating an adrenal crisis. No specific protocol has been studied for AI patients in the context of […]

Written by
06/05/2020

Understanding the Role of Vitamin D

Does vitamin D supplementation have a role in COVID-19? A striking observation about COVID-19 is the greater severity among different populations. Indeed, statistics show that older age, non-Caucasian individuals, male gender, obesity and patients with multiple comorbidities have poorer outcomes. Moreover, most respiratory viruses peak during winter. Vitamin D deficiency, which is more prevalent in […]

Written by
05/17/2020

Is Obesity a Risk Factor for Severity?

In the 2009 H1N1 pandemic, obesity was identified as a risk factor for fatal and critical complications of influenza.1,3,4 Obesity appears to be an independent risk factor for severe COVID-19 infection: 5 The need for invasive mechanical ventilation increases with body mass categories, reaching nearly 90% in ICU patients with a BMI > 35 kg/m2. […]

Written by and
05/10/2020

Is Testosterone a Good or a Bad Guy?

Worldwide epidemiology studies have found higher number of cases of SARS-CoV-2 in men. Moreover, male gender carries a worse prognosis, especially in younger adults. Two opposing theories about androgens have been proposed to explain the gender gap. Testosterone as a promoter of COVID-19 infection: Transmembrane protease serine 2 (TMPRSS2) is a cellular co-receptor required for […]

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05/11/2020

Considerations in the Management of Diabetes in the Pandemic Context

Diabetes is an important risk factor for poorer outcomes in COVID-19. Mechanistic hypotheses include the effect of acute and chronic hyperglycemia on angiotensin-converting-enzyme-2 receptor, impaired immune response and confounding population characteristics such as age and cardiovascular comorbidities. Prevention: Patients at risk of metabolic disease who have contracted the infection should be monitored to prevent new […]

Written by
05/04/2020