Older age, neutrophilia, hepatic and coagulation dysfunction (eg, higher LDH, higher D-dimer) increase risk of developping ARDS and death.
- Diabetes and Hypertension increase risk of developping ARDS without any impact on death.
- High temperature (more than 39°C) increase risk of developping ARDS, but improve chance of survival
- Among ARDS patients, methylprednisolone seemed to reduce the risk of death. (Caution: Methylprednisolone was associated with detrimental outcome in other studies)
This data comes from a retrospective study including 201 patients with confirmed COVID-19 pneumonia admitted to Wuhan Jinyintan Hospital in China between December 25, 2019 and January 26, 2020. They studied the characteristics of patients who developed ARDS and those who died among the sample until February 13, 2020.
Wu C., Chen X., Cai Y., et al (13 March 2020). Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Internal Medecine. https://doi.org/10.1001/jamainternmed.2020.0994