- This case series demonstrates pernio-like lesions as a manifestation of COVID-19.
- Patients presenting this skin lesion were generally young, with few comorbidities, and had relatively benign clinical courses.
- It presented as the sole symptom in 55% of patients.
- In patients with other COVID-19 symptoms, pernio-like lesions typically appeared concurrently or after other symptoms.
- Lesions in this series lasted a median of 14 days.
- Pernio-like lesions should be considered in testing criteria for COVID-19 and prompt consideration for testing for both PCR and IgM and IgG antibodies.
These statements come from analysis of an international dermatology registry circulated to healthcare providers worldwide through the American Academy of Dermatology (AAD), International League of Dermatologic Societies (ILDS), and other organizations. They documented 505 patients with dermatologic lesions associated with COVID-19, including 318 (63%) with pernio-like skin manifestations. This international case series is currently the largest and most comprehensive collection of pernio-like lesions cases as a cutaneous manifestation of confirmed or suspected COVID-19.
Freeman EE., McMahon DE., Lipoff JB., et al (May 29, 2020) Pernio-like lesions associated with COVID-19: a case series of 318 patients from 8 countries, Journal of American Academy of Dermatology. https://doi.org/10.1016/j.jaad.2020.05.109